|
KMID : 1038820220250050432
|
|
Pediatric Gastroenterology, Hepatology & Nutrition
2022 Volume.25 No. 5 p.432 ~ p.440
|
|
|
Cardiac Complications Associated with Eating Disorders in Children: A Multicenter Retrospective Study
|
|
Choi So-Yoon
Lee Kyung-Jae
Kim Soon-Chul
Lee Eun-Hye
Lee Yoo-Min
Kim Yu-Bin
Yi Dae-Yong
Kim Ju-Young
Kang Ben
Jang Hyo-Jeong
Hong Suk-Jin
Choi You-Jin
Kim Hyun-Jin
|
|
|
Abstract
|
|
|
Purpose: Eating disorders often result in somatic complications, including cardiac abnormalities. Cardiac abnormalities may involve any part of the heart, including the cardiac conduction system, and can lead to sudden cardiac death. The current study aimed to evaluate the incidence of cardiac complications in pediatric patients with eating disorders and their associated factors.
Methods: We retrospectively analyzed patients aged 10?18 years who were diagnosed with DSM-V (Diagnostic and Statistical Manual of Mental Disorder-V) eating disorders and underwent electrocardiography (ECG) and/or echocardiography between January 2015 and May 2020.
Results: In total, 127 patients were included, of whom 113 (89.0%) were female. The median body mass index (BMI) was 15.05±3.69 kg/m2. Overall, 74 patients (58.3%) had ECG abnormalities, with sinus bradycardia being the most common abnormality (91.9%). Patients with ECG abnormalities had significantly lower BMI (14.35±2.78 kg/m2 vs. 16.06± 4.55 kg/m2,p<0.001) than patients without ECG abnormalities, as well as lower phosphorus and higher cholesterol levels. Among the 46 patients who underwent echocardiographic evaluation, 23 (50.0%) had echocardiographic abnormalities, with pericardial effusion being the most common (60.9%). The median left ventricular mass (LVM) and ejection fraction were 67.97±21.25 g and 66.91±28.76%, respectively. LVM and BMI showed a positive correlation (r=0.604, p<0.001). After weight gain, the amount of pericardial effusion was reduced in 3 patients, and 30 patients presented with normal ECG findings.
Conclusion: Cardiac abnormalities are relatively frequent in patients with eating disorders. Physicians should focus on this somatic complication and careful monitoring is required.
|
|
|
KEYWORD
|
|
|
Feeding and eating disorders, Cardiovascular diseases, Pericardial effusion, Bradycardia
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
 
|
|